Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 12/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048984 | 0.86 | KDM4E (0.40) | LMNAMAPTCTSSCYP3A4CYP2C9 | |
| SCHEMBL6467567 | 0.79 | CTSS (0.38) | LMNAMAPTCTSSCYP3A4CYP2C9 | |
| SCHEMBL6061692 | 0.79 | CTSS (0.41) | LMNACTSSCYP3A4CYP2C9 | |
| SCHEMBL6475534 | 0.78 | SMN1; SMN2 (0.39) | LMNAMAPTCTSSCYP3A4CYP2C9 | |
| SCHEMBL7047104 | 0.77 | LMNA (0.45) | LMNACTSSCYP3A4 | |
| SCHEMBL7048379 | 0.77 | CTSS (0.41) | LMNACTSSCYP3A4CYP2C9 | |
| SCHEMBL7043345 | 0.76 | CTSS (0.47) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6466063 | 0.75 | KDM4E (0.41) | MAPTCTSSCYP3A4CYP2C9 | |
| SCHEMBL7045499 | 0.73 | ELANE (0.43) | MAPTATM | |
| SCHEMBL7046968 | 0.72 | ELANE (0.44) | LMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |