Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.38 |
| ▸ | GART | P22102 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466913 | 0.88 | FAAH (0.41) | KDM4EPOLBCTSSGARTALDH1A1 | |
| SCHEMBL7048984 | 0.80 | KDM4E (0.40) | KDM4EPOLBCTSSGARTMAPT | |
| SCHEMBL6464310 | 0.77 | ALDH1A1 (0.41) | KDM4EPOLBCTSSGARTALDH1A1 | |
| SCHEMBL6463422 | 0.76 | FAAH (0.41) | CTSSGARTMAPTHTTFAAH | |
| SCHEMBL7181305 | 0.75 | LMNA (0.42) | CTSSMAPTCYP3A4CYP2C9 | |
| SCHEMBL6471951 | 0.74 | XDH (0.43) | KDM4ECTSSGARTFAAHCES1 | |
| SCHEMBL6465893 | 0.73 | GART (0.43) | KDM4ECTSSGARTFAAHCES1 | |
| SCHEMBL6461911 | 0.71 | FAAH (0.42) | CTSSGARTMAPTHTTFAAH | |
| SCHEMBL11078276 | 0.70 | DCAF1 (0.43) | MAPTALDH1A1 | |
| SCHEMBL6465159 | 0.68 | FAAH (0.44) | CTSSGARTALDH1A1FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |