Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | LTA4H | P09960 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.64 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.64 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685423 | 0.85 | TBXAS1 (0.80) | TBXAS1KMT2AMEN1LMNALTA4H | |
| SCHEMBL3777816 | 0.84 | TBXAS1 (1.00) | TBXAS1KMT2AMEN1LMNALTA4H | |
| Dazoxiben SCHEMBL11554 | 0.83 | TBXAS1 (1.00) | TBXAS1KMT2AMEN1LMNAALDH1A1 | |
| Dazoxiben SCHEMBL4427771 | 0.82 | TBXAS1 (0.97) | TBXAS1KMT2AMEN1LMNAALDH1A1 | |
| Dazoxiben SCHEMBL564080 | 0.82 | TBXAS1 (1.00) | TBXAS1KMT2AMEN1LMNA | |
| SCHEMBL10749397 | 0.82 | TBXAS1 (1.00) | TBXAS1KMT2AMEN1LMNALTA4H | |
| SCHEMBL7132156 | 0.81 | LTA4H (1.00) | TBXAS1KMT2AMEN1LMNALTA4H | |
| SCHEMBL10370478 | 0.80 | TBXAS1 (1.00) | TBXAS1KMT2AMEN1LMNALTA4H | |
| SCHEMBL3005716 | 0.80 | TBXAS1 (1.00) | TBXAS1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8690308 | 0.80 | TBXAS1 (0.78) | TBXAS1KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576645-B1 | Such as 3-(4-chloro-1-(4-(2-(2-hydroxyethoxy)ethoxy)phenyl)--2-phenylbut-1 -enyl)phenol; producing tissue specific estro-genic and/or antiestrogenic effect | HORMOS MEDICAL OY LTD (FI) | 2003-06-10 | — | — | US | disclosed |