Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181577 | 1.00 | MEN1 (0.45) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL4328150 | 0.82 | THRB (0.43) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL4328153 | 0.82 | THRB (0.43) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL10720203 | 0.82 | TYMS (0.56) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL373836 | 0.81 | MAPT (0.45) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL1802827 | 0.81 | MAPT (0.45) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL14130394 | 0.80 | MAPT (0.50) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL21657884 | 0.79 | IDE (0.42) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL14130172 | 0.79 | KMT2A (0.46) | MEN1KMT2AL3MBTL1MAPTNPC1 | |
| SCHEMBL14130409 | 0.77 | KMT2A (0.50) | MEN1KMT2AL3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722110-B1 | Water absorptive soft contact lens | MENICON CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-5661194-A | POLYMER FROM MONOMERS OF (METH)ACRYLAMIDE TYPE MONOMER, FLUOROALKYL (SILICON-CONTAINING ALKYL) FUMARATE MONOMER, AND CROSSLINKING MONOMER | MENICON CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0722110-A2 | Water absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-07-17 | — | — | EP | disclosed |