Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626178 | 0.88 | TSHR (0.46) | — | |
| SCHEMBL820953 | 0.88 | TSHR (0.46) | — | |
| SCHEMBL9233304 | 0.86 | SIGMAR1 (0.46) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL3342120 | 0.82 | SIGMAR1 (0.43) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL8071187 | 0.82 | IDO1 (0.45) | SIGMAR1IDO1 | |
| SCHEMBL11090030 | 0.79 | SIGMAR1 (0.41) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL22630205 | 0.79 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19090603 | 0.79 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL108633 | 0.79 | LMNA (0.54) | SIGMAR1 | |
| SCHEMBL8062696 | 0.78 | IDO1 (0.42) | SIGMAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282615-A1 | CHROMAN DERIVATIVES AS ESTROGENIC COMPOUNDS | Akzo Nobel N.V. (NL) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001064665-A1 | CHROMAN DERIVATIVES AS ESTROGENIC COMPOUNDS | AKZO NOBEL N.V. (NL) | 2001-09-07 | — | — | WO | disclosed |