Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176769 | 1.00 | F10 (0.38) | F10KMT2AMEN1ATMMAPT | |
| SCHEMBL6570397 | 0.91 | KMT2A (0.42) | KMT2AMEN1LMNAPOLBTDP1 | |
| SCHEMBL6570389 | 0.91 | KMT2A (0.42) | KMT2AMEN1LMNAPOLBTDP1 | |
| SCHEMBL6570448 | 0.89 | L3MBTL1 (0.37) | F10KMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL6570451 | 0.89 | L3MBTL1 (0.37) | F10KMT2ALMNATDP1L3MBTL1 | |
| Timcodar SCHEMBL3673444 | 0.89 | L3MBTL1 (0.37) | F10KMT2ALMNATDP1L3MBTL1 | |
| Timcodar SCHEMBL1492143 | 0.89 | L3MBTL1 (0.37) | F10KMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL6572477 | 0.88 | SLC2A1 (0.39) | F10KMT2AMEN1ATMMAPT | |
| SCHEMBL6570405 | 0.88 | SLC2A1 (0.39) | F10KMT2AMEN1ATMMAPT | |
| SCHEMBL8463579 | 0.86 | MAPT (0.35) | F10KMT2AMEN1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946190-B1 | METHODS AND COMPOSITIONS FOR STIMULATING NEURITE OUTGROWTH | VERTEX PHARMA (US) | 2003-09-24 | — | — | EP | claimed |