Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472382 | 0.89 | LPAR1 (0.39) | MAPTL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL1492154 | 0.89 | LPAR1 (0.39) | MAPTL3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL8780679 | 0.89 | SLC2A1 (0.39) | MAPTF10L3MBTL1KMT2AMEN1 | |
| SCHEMBL7181772 | 0.86 | F10 (0.38) | MAPTF10L3MBTL1KMT2AMEN1 | |
| SCHEMBL7176769 | 0.86 | F10 (0.38) | MAPTF10L3MBTL1KMT2AMEN1 | |
| SCHEMBL8466536 | 0.83 | CYP1A2 (0.35) | LMNAALDH1A1TP53 | |
| Timcodar SCHEMBL1492143 | 0.81 | L3MBTL1 (0.37) | F10L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL6570451 | 0.81 | L3MBTL1 (0.37) | F10L3MBTL1KMT2ALMNAALDH1A1 | |
| Timcodar SCHEMBL3673444 | 0.81 | L3MBTL1 (0.37) | F10L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL6570448 | 0.81 | L3MBTL1 (0.37) | F10L3MBTL1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946190-A1 | METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS | Vertex Pharmaceuticals Incorporated (US) | 1999-10-06 | — | — | EP | claimed |
| WO-1998020891-A1 | METHODS AND COMPOSITIONS FOR STIMULATING NEURITE GROWTH USING COMPOUNDS WITH AFFINITY FOR FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1998-05-22 | — | — | WO | claimed |