Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857963 | 0.87 | GAA (0.54) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| SCHEMBL285169 | 0.79 | KDM4E (0.51) | KDM4ENPC1RAB9AHPGDPOLB | |
| SCHEMBL29435921 | 0.78 | RAB9A (0.69) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| SCHEMBL413259 | 0.78 | RAB9A (0.69) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| SCHEMBL413260 | 0.78 | RAB9A (0.69) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| SCHEMBL7609308 | 0.77 | SMN1; SMN2 (0.76) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| Bicarbonate SCHEMBL11140372 | 0.76 | FAAH (0.53) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| SCHEMBL5708151 | 0.75 | MAPT (0.55) | KDM4ENPC1RAB9APOLBALDH1A1 | |
| SCHEMBL152658 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4ENPC1RAB9AHPGD | |
| SCHEMBL29362501 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4ENPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325067-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2002031035-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2002-04-18 | — | — | WO | claimed |
| EP-0220576-B1 | STAINPROOF POLYESTER FIBER | TEIJIN LIMITED (JP) | 1991-01-02 | — | — | EP | disclosed |