SCHEMBL5708151

SCHEMBL5708151

C(=C(c1nc2ccccc2o1)c1nc2ccccc2o1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.55
KDM4E B2RXH2 7/20 0.55
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.55
RAB9A P51151 3/20 0.55
MAPK1 P28482 2/20 0.55
NPC1 O15118 2/20 0.55
HTT P42858 4/20 0.54
FAAH O00519 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
POLB P06746 2/20 0.52
NPSR1 Q6W5P4 2/20 0.51
GLO1 Q04760 1/20 0.50
XDH P47989 2/20 0.48
ALDH1A1 P00352 4/20 0.47
GAA P10253 3/20 0.47
LMNA P02545 3/20 0.47
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
CES1 P23141 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285169 0.92 KDM4E (0.51) MAPTKDM4EKMT2AMEN1RAB9A
Bicarbonate SCHEMBL11140372 0.88 FAAH (0.53) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL476618 0.80 KDM4E (0.49) MAPTKDM4EKMT2AMEN1RAB9A
Serine SCHEMBL2917580 0.78 KDM4E (0.46) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL2494950 0.76 KDM4E (0.48) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL8032979 0.76 XDH (0.54) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL1857963 0.75 GAA (0.54) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL11148950 0.74 XDH (0.47) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL1590095 0.74 FAAH (0.55) MAPTKDM4EKMT2AMEN1RAB9A
SCHEMBL458166 0.74 XDH (0.49) MAPTKDM4EKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180320098-A1 PROCESS FOR ENHANCING GASOLINE OCTANE BOOSTERS, GASOLINE BOOSTERS, AND GASOLINES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-11-08 US disclosed
EP-3383977-A1 PROCESS FOR ENHANCING GASOLINE OCTANE BOOSTERS, GASOLINE BOOSTERS, AND GASOLINES SABIC Global Technologies B.V. (NL) 2018-10-10 EP disclosed
WO-2017093913-A1 PROCESS FOR ENHANCING GASOLINE OCTANE BOOSTERS, GASOLINE BOOSTERS, AND GASOLINES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-08 WO disclosed
EP-1325067-B1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
EP-1325067-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2003-07-09 EP disclosed
US-6492032-B1 MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS EASTMAN CHEMICAL COMPANY 2002-12-10 US disclosed
WO-2002031035-A1 MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND EASTMAN CHEMICAL COMPANY (US) 2002-04-18 WO disclosed
EP-0058880-B1 MIXTURES OF OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-30 EP disclosed
US-4416795-A Mixtures of optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-22 US disclosed
EP-0058880-A1 Mixtures of optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-01 EP disclosed