SCHEMBL7182

SCHEMBL7182

CCOC(=O)[C@@H]1C[C@H]1c1ccc(Br)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
MAPT P10636 2/20 0.46
PKM P14618 1/20 0.46
FPR2 P25090 1/20 0.44
HRH3 Q9Y5N1 2/20 0.43
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
CA12 O43570 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 1/20 0.42
S1PR4 O95977 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439856 1.00 TSHR (0.48) TSHRHTTMAPTPKMFPR2
SCHEMBL6256 1.00 TSHR (0.48) TSHRHTTMAPTPKMFPR2
SCHEMBL6257 1.00 TSHR (0.48) TSHRHTTMAPTPKMFPR2
SCHEMBL1000358 1.00 TSHR (0.48) TSHRHTTMAPTPKMFPR2
SCHEMBL6082774 0.87 ALDH1A1 (0.55) HTTMAPTPKMALDH1A1CYP1A2
SCHEMBL15977387 0.87 ALDH1A1 (0.55) HTTMAPTPKMALDH1A1CYP1A2
SCHEMBL15235893 0.87 ALDH1A1 (0.55) HTTMAPTPKMALDH1A1CYP1A2
SCHEMBL14870924 0.87 MAPT (0.50) TSHRHTTMAPTPKMMAPK1
SCHEMBL15428491 0.86 MAPT (0.47) TSHRMAPTPKMALDH1A1CA1
SCHEMBL433974 0.86 MAPT (0.47) TSHRMAPTPKMALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3974481-A1 FOULING RELEASE COATING COMPOSITION Jotun A/S (NO) 2022-03-30 EP claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
EP-2776162-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-01-04 EP claimed
US-9523002-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-12-20 US claimed
WO-2016137881-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES (US) 2016-09-01 WO claimed
US-20160244606-A1 CURABLE COATING COMPOSITIONS OF SILANE FUNCTIONAL POLYMERS KING INDUSTRIES 2016-08-25 US claimed
US-9394443-B2 Moisture curable organopolysiloxane composition MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2016-07-19 US claimed
US-20140378612-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2014-12-25 US claimed
US-20140343202-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2014-11-20 US claimed
EP-2797986-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-11-05 EP claimed
US-20140316059-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2014-10-23 US claimed
EP-2776162-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-09-17 EP claimed
EP-2614107-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2013-07-17 EP claimed
WO-2013101751-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013071078-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-05-16 WO claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
WO-2012033886-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-15 WO claimed
EP-4385086-A2 SECONDARY BATTERY PACK WITH IMPROVED THERMAL MANAGEMENT Elkem Silicones USA Corp. (US) 2024-06-19 EP disclosed
WO-2004048374-A1 4-OXO-1-(3-SUBSTITUTED PHENYL-1,4-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXAMIDE PHOSPHODIESTERASE-4 INHIBITORS MERCK FROSST CANADA & CO. (CA) 2004-06-10 WO disclosed
WO-2004000814-A1 8-(BIARYL) QUINOLINE PDE4 INHIBITORS MERCK FROSST CANADA & CO. (CA) 2003-12-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343202-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION TST, SMCHD1, SBDS TSHR 2140/4885HTT 375/4885MAPT 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.