Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL811295 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7175041 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7176154 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7174397 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL5693547 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7177207 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL817480 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7185143 | 0.97 | PAX8 (0.35) | PAX8HSP90AA1MEN1KMT2AATM | |
| SCHEMBL453477 | 0.97 | HSP90AA1 (0.36) | PAX8HSP90AA1MEN1KMT2AATM | |
| SCHEMBL453478 | 0.97 | HSP90AA1 (0.36) | PAX8HSP90AA1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |