Sugi Predict

Sugi Predict / Compounds / SCHEMBL7182275

SCHEMBL7182275

SCHEMBL7182275

Cc1cccc(C)c1C(=O)c1ccccc1[P](=O)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C9 P11712 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ CYP3A4 P08684 2/20 0.37
▸ MYC P01106 1/20 0.36
▸ HPGD P15428 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ POLB P06746 1/20 0.33
▸ RORC P51449 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ FLT1 P17948 1/20 0.33
▸ FLT4 P35916 1/20 0.33
▸ KDR P35968 1/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ AKR1B10 O60218 1/20 0.33
▸ TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7178175 0.88 KMT2A (0.40) KMT2AHPGDALDH1A1KDM4EHSD17B10
SCHEMBL7183502 0.83 CNR2 (0.38) CYP2C9CYP3A4ALDH1A1POLBRORC
SCHEMBL7175729 0.82 ALDH1A1 (0.32) CYP2C9KMT2ACYP3A4HPGDALDH1A1
SCHEMBL7174817 0.81 CA12 (0.44) RORCMAPTCNR2HTTELANE
SCHEMBL7181687 0.81 LMNA (0.40) CYP2C9KMT2ACYP3A4ALDH1A1RORC
SCHEMBL7190118 0.78 CNR2 (0.38) CYP2C9KMT2ACYP3A4MYCHPGD
SCHEMBL7183698 0.76 CYP3A4 (0.40) KMT2ACYP3A4HPGDALDH1A1KDM4E
SCHEMBL7181274 0.76 ALDH1A1 (0.32) CYP2C9KMT2ACYP3A4MYCHPGD
SCHEMBL7041793 0.75 CYP3A4 (0.48) CYP2C9KMT2ACYP3A4MYCHPGD
SCHEMBL7185548 0.75 F2R (0.36) CYP2C9KMT2ACYP3A4MYCHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 CYP2C9 1094/4885KMT2A 1586/4885CYP3A4 1652/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 CYP2C9 1606/4885KMT2A 956/4885CYP3A4 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.