Sugi Predict

Sugi Predict / Compounds / SCHEMBL7185548

SCHEMBL7185548

SCHEMBL7185548

Cc1cccc(C)c1C(=O)c1ccccc1[P](=O)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F2R P25116 1/20 0.36
▸ KMT2A Q03164 2/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ ALDH1A1 P00352 5/20 0.35
▸ MAPT P10636 2/20 0.35
▸ GAA P10253 1/20 0.35
▸ CNR1 P21554 5/20 0.34
▸ CNR2 P34972 5/20 0.34
▸ TSHR P16473 2/20 0.34
▸ MYC P01106 1/20 0.33
▸ FLT1 P17948 1/20 0.33
▸ FLT4 P35916 1/20 0.33
▸ KDR P35968 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HPGD P15428 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NR1I2 O75469 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179788 0.89 HPGD (0.43) F2RKMT2AALDH1A1MAPTCNR1
SCHEMBL7181597 0.87 P2RX7 (0.36) F2RKMT2ACYP3A4CYP2C9ALDH1A1
SCHEMBL7181274 0.85 ALDH1A1 (0.32) F2RKMT2ACYP3A4CYP2C9ALDH1A1
SCHEMBL7186443 0.84 CNR2 (0.39) KMT2ACYP3A4CYP2C9ALDH1A1GAA
SCHEMBL7180640 0.84 ALDH1A1 (0.34) F2RKMT2AALDH1A1CNR1CNR2
SCHEMBL7187696 0.82 CA12 (0.41) KMT2AALDH1A1L3MBTL1HPGDHTT
SCHEMBL7180550 0.81 LMNA (0.36) F2RCYP3A4CYP2C9ALDH1A1GAA
SCHEMBL7190118 0.81 CNR2 (0.38) KMT2ACYP3A4CYP2C9ALDH1A1MAPT
SCHEMBL7185614 0.80 ALDH1A1 (0.44) CYP3A4ALDH1A1CNR1CNR2TSHR
SCHEMBL7189509 0.79 CNR2 (0.35) F2RKMT2ACYP3A4CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 F2R 4532/4885KMT2A 1586/4885CYP3A4 1652/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 F2R 4423/4885KMT2A 956/4885CYP3A4 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.