Sugi Predict

Sugi Predict / Compounds / SCHEMBL7182437

SCHEMBL7182437

SCHEMBL7182437

Cc1cc(C)c(C(=O)Pc2ccc(OCC(C)C)cc2OCC(C)C)c(C)c1.[LiH]

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOS P01100 2/20 0.38
▸ JUN P05412 2/20 0.38
▸ XDH P47989 1/20 0.38
▸ KEAP1 Q14145 1/20 0.36
▸ NFE2L2 Q16236 1/20 0.36
▸ FFAR1 O14842 1/20 0.35
▸ PPARD Q03181 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ ACACB O00763 4/20 0.33
▸ PDK2 Q15119 1/20 0.33
▸ ABL1 P00519 1/20 0.33
▸ ITGB1 P05556 1/20 0.33
▸ ITGA4 P13612 1/20 0.33
▸ TP53 P04637 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL7182446 0.98 KEAP1 (0.36) FOSJUNXDHKEAP1NFE2L2
SCHEMBL7188508 0.91 FOS (0.41) FOSJUNXDHKEAP1NFE2L2
SCHEMBL7188227 0.90 XDH (0.39) FOSJUNXDHFFAR1PPARD
SCHEMBL7177986 0.90 FOS (0.36) FOSJUNXDHKEAP1NFE2L2
SCHEMBL7184514 0.89 FOS (0.38) FOSJUNXDHKEAP1NFE2L2
Lithium SCHEMBL7188514 0.88 FFAR1 (0.39) FOSJUNXDHKEAP1NFE2L2
Lithium SCHEMBL7177991 0.87 FOS (0.34) FOSJUNXDHKEAP1NFE2L2
Lithium SCHEMBL7184526 0.87 FOS (0.35) FOSJUNXDHKEAP1NFE2L2
SCHEMBL7182736 0.86 MAPK1 (0.41) PDK2ITGB1ITGA4TP53GAA
SCHEMBL7182284 0.84 KDM4E (0.45) XDHALDH1A1TP53GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 FOS 2702/4885JUN 4136/4885XDH 4277/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 FOS 2549/4885JUN 3781/4885XDH 4546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.