SCHEMBL7182472

SCHEMBL7182472

CCOCCOc1ccc(PC(=O)c2c(Cl)cccc2Cl)c(OCCOCC)c1.[LiH]

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.44
FFAR1 O14842 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
KDM4E B2RXH2 4/20 0.38
APP P05067 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 1/20 0.37
PTGES O14684 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
THRA P10827 1/20 0.36
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182538 0.95 L3MBTL1 (0.43) L3MBTL1LMNAMAPTFFAR1MEN1
SCHEMBL7187640 0.95 FFAR1 (0.41) L3MBTL1LMNAMAPTFFAR1MEN1
SCHEMBL7187590 0.90 KMT2A (0.43) L3MBTL1LMNAMAPTMEN1KMT2A
SCHEMBL7182885 0.90 FAAH (0.41) L3MBTL1MEN1KMT2AALDH1A1TDP1
SCHEMBL7180645 0.89 LMNA (0.44) L3MBTL1LMNAMAPTFFAR1MEN1
SCHEMBL7180243 0.89 FFAR1 (0.46) L3MBTL1LMNAMAPTFFAR1MEN1
SCHEMBL7177487 0.88 L3MBTL1 (0.41) L3MBTL1LMNAMAPTFFAR1KDM4E
SCHEMBL7187392 0.88 MAPT (0.46) L3MBTL1LMNAMAPTMEN1KMT2A
SCHEMBL7186779 0.87 PLA2G4B (0.43) THRA
Lithium SCHEMBL7187598 0.87 KMT2A (0.43) L3MBTL1LMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 L3MBTL1 302/4885LMNA 3241/4885MAPT 4870/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 L3MBTL1 126/4885LMNA 3247/4885MAPT 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.