Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799303 | 1.00 | RORC (0.38) | RORCDRD4MGLLKDM4EKMT2A | |
| SCHEMBL4799313 | 1.00 | RORC (0.38) | RORCDRD4MGLLKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL4802092 | 0.99 | KDM4E (0.38) | RORCDRD4MGLLKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL4802073 | 0.99 | KDM4E (0.38) | RORCDRD4MGLLKDM4EKMT2A | |
| Fumaric Acid SCHEMBL4796843 | 0.93 | MGLL (0.39) | RORCMGLLKDM4EKMT2ASIGMAR1 | |
| Maleic Acid SCHEMBL4796837 | 0.93 | MGLL (0.39) | RORCMGLLKDM4EKMT2ASIGMAR1 | |
| SCHEMBL14180280 | 0.84 | DRD4 (0.38) | RORCDRD4MGLLKDM4EKMT2A | |
| SCHEMBL4800637 | 0.77 | MEN1 (0.47) | RORCKMT2A | |
| SCHEMBL7180636 | 0.76 | TACR2 (0.43) | RORCDRD4MGLLKDM4EKMT2A | |
| SCHEMBL7174179 | 0.76 | TACR2 (0.43) | RORCDRD4MGLLKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200417-B1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1200417-A1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004105-A1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2001-01-18 | — | — | WO | disclosed |