Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7172480 | 0.97 | TRPV1 (0.34) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7176863 | 0.97 | TRPV1 (0.34) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7177457 | 0.97 | TRPV1 (0.34) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7178920 | 0.97 | TRPV1 (0.34) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7178223 | 0.97 | TRPV1 (0.34) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7171420 | 0.97 | TRPV1 (0.34) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7183693 | 0.90 | TLR8 (0.33) | TRPV1TLR8MAPK1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7178976 | 0.89 | GRIN2D (0.32) | — | |
| Hydrochloric Acid SCHEMBL7177253 | 0.89 | KCNH2 (0.37) | TRPV1TLR8RAB9AHTTKCNH2 | |
| Hydrochloric Acid SCHEMBL7178990 | 0.87 | TLR8 (0.33) | TRPV1TLR8MAPK1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |