Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 14/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048562 | 0.89 | LMNA (0.48) | LMNAHTTSMN1; SMN2CTSSCTSL | |
| SCHEMBL7047998 | 0.85 | LMNA (0.46) | LMNAHTTSMN1; SMN2CTSSMAPT | |
| SCHEMBL7042876 | 0.82 | CTSS (0.43) | LMNAHTTSMN1; SMN2CTSSCTSL | |
| Hydrochloric Acid SCHEMBL7114471 | 0.81 | CTSS (0.43) | LMNAHTTSMN1; SMN2CTSSCTSL | |
| SCHEMBL7047104 | 0.81 | LMNA (0.45) | LMNAHTTSMN1; SMN2CTSSCYP3A4 | |
| SCHEMBL6062139 | 0.81 | CTSS (0.45) | LMNAHTTSMN1; SMN2CTSSCTSL | |
| SCHEMBL7183396 | 0.81 | CTSS (0.44) | LMNAHTTSMN1; SMN2CTSSCTSL | |
| SCHEMBL7046461 | 0.80 | ELANE (0.43) | HTTELANE | |
| SCHEMBL7112203 | 0.79 | CTSS (0.56) | LMNAHTTSMN1; SMN2CTSSCTSL | |
| SCHEMBL7045283 | 0.78 | CTSS (0.57) | LMNAHTTSMN1; SMN2CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |