Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 12/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048562 | 0.91 | LMNA (0.48) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6062139 | 0.91 | CTSS (0.45) | CTSSCTSLCTSBCTSKPTGES | |
| SCHEMBL7112203 | 0.90 | CTSS (0.56) | CTSSCTSLCTSBCTSKPTGES | |
| SCHEMBL7045283 | 0.88 | CTSS (0.57) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL6464575 | 0.87 | LMNA (0.44) | LMNASMN1; SMN2KMT2ACASP3FFAR2 | |
| SCHEMBL7046658 | 0.86 | CTSL (0.39) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL7049752 | 0.81 | KMT2A (0.43) | LMNASMN1; SMN2KMT2ACASP3FFAR2 | |
| SCHEMBL7183138 | 0.81 | LMNA (0.45) | CTSSCTSLCTSBCTSKLMNA | |
| SCHEMBL7049421 | 0.78 | CTSL (0.44) | CTSSCTSLCTSBCTSKPTGES | |
| SCHEMBL7046158 | 0.78 | LMNA (0.40) | CTSSCTSLCTSBCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |