Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.55 |
| ▸ | CTSL | P07711 | 10/20 | 0.55 |
| ▸ | CTSB | P07858 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045971 | 0.87 | CTSS (0.64) | CTSSCTSLCTSB | |
| SCHEMBL6464251 | 0.85 | REN (0.41) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6463634 | 0.83 | FPR2 (0.47) | CTSSCTSLCTSB | |
| SCHEMBL6063087 | 0.80 | CTSS (0.64) | CTSSCTSLCTSB | |
| SCHEMBL7109606 | 0.76 | CTSS (0.48) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7044867 | 0.76 | CTSS (0.48) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7043449 | 0.75 | CTSS (0.63) | CTSSCTSLCTSBCTSK | |
| SCHEMBL8291073 | 0.73 | CTSS (0.60) | CTSSCTSLCTSBCTSK | |
| SCHEMBL5946042 | 0.73 | CTSS (0.47) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7047934 | 0.72 | CTSS (0.46) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |