Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187298 | 0.98 | DGKA (0.43) | CA1CA2GAANPSR1DGKA | |
| SCHEMBL7182276 | 0.98 | DGKA (0.43) | CA1CA2GAANPSR1DGKA | |
| SCHEMBL7184752 | 0.98 | DGKA (0.43) | CA1CA2GAANPSR1DGKA | |
| SCHEMBL8208205 | 0.89 | ALDH1A1 (0.46) | CA1CA2GAADGKAMEN1 | |
| SCHEMBL7057715 | 0.88 | ALDH1A1 (0.48) | CA1CA2GAADGKAMEN1 | |
| SCHEMBL28415270 | 0.88 | HSD17B3 (0.51) | DGKAKMT2ALMNA | |
| SCHEMBL28416008 | 0.88 | HSD17B3 (0.51) | DGKAKMT2ALMNA | |
| SCHEMBL8210289 | 0.88 | ALDH1A1 (0.48) | CA1CA2GAADGKAMEN1 | |
| SCHEMBL27588753 | 0.88 | CA1 (0.43) | CA1CA2GAADGKAMEN1 | |
| SCHEMBL8542959 | 0.87 | MEN1 (0.50) | CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083167-B1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEM CO (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1083167-A1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |