Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 4/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182276 | 1.00 | DGKA (0.43) | DGKACA1CA2CES2CES1 | |
| SCHEMBL7187298 | 1.00 | DGKA (0.43) | DGKACA1CA2CES2CES1 | |
| SCHEMBL7183376 | 0.98 | CA1 (0.42) | DGKACA1CA2CES2CES1 | |
| SCHEMBL7057715 | 0.89 | ALDH1A1 (0.48) | DGKACA1CA2LMNAGAA | |
| SCHEMBL28416008 | 0.89 | HSD17B3 (0.51) | DGKALMNAALDH1A1 | |
| SCHEMBL28415270 | 0.89 | HSD17B3 (0.51) | DGKALMNAALDH1A1 | |
| SCHEMBL8210289 | 0.89 | ALDH1A1 (0.48) | DGKACA1CA2LMNAGAA | |
| Ammonia Solution, Strong SCHEMBL27383584 | 0.88 | ALDH1A1 (0.47) | DGKACA1CA2LMNAGAA | |
| SCHEMBL29664380 | 0.88 | ALDH1A1 (0.51) | DGKACA1CA2CES2CES1 | |
| SCHEMBL7290861 | 0.88 | MEN1 (0.49) | DGKACES2CES1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083167-B1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEM CO (US) | 2003-04-16 | — | — | EP | disclosed |
| US-6448430-B1 | BY REACTION OF A PHENOL WITH A CARBOXYLIC ACID IN THE PRESENCE OF TRIFLUOROACETIC ACID (TFA) AND TRIFLUOROACETIC ANHYDRIDE (TFAA); RELATIVELY LOW TEMPERATURE | EASTMAN CHEMICAL COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1083167-A1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |