Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 5/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183522 | 0.92 | MAT2A (0.47) | MAT2ATNKS2LRRK2GABRPGABRD | |
| SCHEMBL7190963 | 0.83 | MAT2A (0.47) | MAT2ATNKS2MAP3K11QPCTIDO1 | |
| SCHEMBL11134 | 0.78 | PRKCI (0.53) | ADORA2AHSD11B1 | |
| SCHEMBL29424823 | 0.78 | PRKCI (0.53) | ADORA2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL3671411 | 0.76 | KDM4E (0.55) | ADORA2AHSD11B1 | |
| SCHEMBL27252266 | 0.76 | TNKS2 (0.50) | MAT2ATNKS2LRRK2GABRPGABRD | |
| SCHEMBL7190954 | 0.76 | MAP3K11 (0.39) | MAT2ATNKS2MAP3K11LRRK2QPCT | |
| SCHEMBL31435021 | 0.76 | MEN1 (0.62) | MAT2ATNKS2LRRK2MEN1LMNA | |
| SCHEMBL20302464 | 0.73 | L3MBTL1 (0.46) | TNKS2MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL7190679 | 0.71 | MAPT (0.53) | MAT2AQPCTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |