SCHEMBL7183545

SCHEMBL7183545

CCCCCCCCCCCCCCCCC(C(N)=O)C(C)C(CCCCCCCCCCCCCCCC)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
ACE2 Q9BYF1 1/20 0.46
GPR84 Q9NQS5 6/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 2/20 0.45
SPHK1 Q9NYA1 1/20 0.45
FFAR1 O14842 1/20 0.45
MAPT P10636 1/20 0.44
TP53 P04637 1/20 0.44
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
OPRM1 P35372 1/20 0.43
LAP3 P28838 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15329288 0.89 MAPT (0.54) EPHX1ACE2GPR84CA1CA2
SCHEMBL21670103 0.88 EPHX1 (0.48) EPHX1ACE2GPR84CA1CA2
SCHEMBL16393900 0.88 EPHX1 (0.48) EPHX1ACE2GPR84CA1CA2
SCHEMBL31560160 0.88 EPHX1 (0.48) EPHX1ACE2GPR84CA1CA2
SCHEMBL4391098 0.87 CA2 (0.54) EPHX1ACE2GPR84CA1CA2
SCHEMBL6901656 0.86 SPHK1 (0.53) EPHX1ACE2GPR84CA1CA2
SCHEMBL31057932 0.86 EPHX1 (0.47) EPHX1ACE2GPR84CA1CA2
SCHEMBL28723561 0.86 EPHX1 (0.47) EPHX1ACE2GPR84CA1CA2
SCHEMBL572638 0.86 GPR84 (0.48) EPHX1ACE2GPR84CA1CA2
SCHEMBL28723571 0.86 EPHX1 (0.47) EPHX1ACE2GPR84CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735092-B1 Mold material with additives JOHNSON & JOHNSON VISION CARE (US) 2003-09-03 EP disclosed
EP-0765721-A2 Mold material made with additives JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1997-04-02 EP disclosed
EP-0735092-A2 Mold material with additives JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1996-10-02 EP disclosed