SCHEMBL7183570

SCHEMBL7183570

O=C(Pc1ccc(Oc2ccccc2)cc1)c1c(Cl)cccc1Cl.[LiH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 1/20 0.43
LTA4H P09960 2/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
PGR P06401 3/20 0.42
FFAR1 O14842 1/20 0.41
MAPT P10636 3/20 0.41
PTK2B Q14289 1/20 0.41
PARP10 Q53GL7 1/20 0.41
KMO O15229 1/20 0.41
SRD5A2 P31213 2/20 0.41
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AKR1C3 P42330 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7185568 0.92 FABP3 (0.40) DAGLALTA4HNR1H2BAXPGR
SCHEMBL7190107 0.91 CA12 (0.43) DAGLALTA4HPGRMAPTLMNA
SCHEMBL7179685 0.85 ALDH1A1 (0.48) MAPTPTK2BMEN1KMT2ANPSR1
SCHEMBL7180835 0.83 MEN1 (0.43) LTA4HNR1H2BAXFFAR1PARP10
SCHEMBL7174576 0.83 ALDH1A1 (0.50) MAPTPTK2BMEN1KMT2ANPSR1
SCHEMBL7182801 0.83 KMT2A (0.46) MAPTLMNAMEN1KMT2A
SCHEMBL7182551 0.82 LMNA (0.45) FFAR1MAPTLMNAMEN1KMT2A
SCHEMBL7189087 0.81 PTGS1 (0.51) FFAR1PARP10SRD5A2LMNA
SCHEMBL7189098 0.81 CA12 (0.47) LTA4HNR1H2BAXPGRMAPT
SCHEMBL7189899 0.80 KMO (0.42) DAGLAPGRKMOLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 DAGLA 2370/4885LTA4H 3888/4885NR1H2 63/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 DAGLA 1871/4885LTA4H 3948/4885NR1H2 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.