Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22351 | 0.86 | MAPK1 (0.50) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL1421191 | 0.83 | ALDH1A1 (0.54) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL7628903 | 0.81 | MAPK1 (0.45) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL128131 | 0.79 | MAPK1 (0.65) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL7448596 | 0.79 | MAPK1 (0.46) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL3688349 | 0.77 | ALDH1A1 (0.47) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| Hexane SCHEMBL8712556 | 0.75 | ALDH1A1 (0.46) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL7606018 | 0.75 | MAPK1 (0.59) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 | |
| SCHEMBL21681665 | 0.74 | MAPK1 (0.41) | MAPK1TAAR1ALDH1A1ALOX15KCNN4 | |
| SCHEMBL42933 | 0.73 | SHBG (0.60) | MAPK1TAAR1ALDH1A1ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642315-B2 | For use for a tire tread having a superior wet grip and abrasion resistance | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| US-20030055169-A1 | Rubber composition and crosslinked rubber | YOKOHAMA RUBBER CO., LTD., THE (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1245630-A1 | RUBBER COMPOSITION AND CROSSLINKED RUBBER | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2002-10-02 | — | — | EP | disclosed |