Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190670 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7181421 | 0.89 | LMNA (0.38) | PTPN1ABCG2KEAP1NFE2L2BCHE | |
| SCHEMBL7180028 | 0.88 | MAPT (0.43) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7180355 | 0.87 | MAPT (0.42) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7192313 | 0.83 | MAPT (0.45) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7185054 | 0.81 | PTPN1 (0.47) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7185050 | 0.81 | PTPN1 (0.47) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7184621 | 0.78 | CYP1A1 (0.41) | MAPTABCG2BCHECHRNA7 | |
| SCHEMBL7184268 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7184272 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |