SCHEMBL7183770

SCHEMBL7183770

Cc1cccc(C)c1C(=O)Pc1ccc(-c2ccccc2)cc1.[LiH]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
MAPT P10636 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ABCC4 O15439 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
PTGS1 P23219 1/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
MCL1 Q07820 1/20 0.36
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36
CCR5 P51681 1/20 0.36
S1PR4 O95977 1/20 0.36
PTGS2 P35354 1/20 0.36
FFAR1 O14842 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7183622 0.90 L3MBTL1 (0.40) FABP3FABP4SMN1; SMN2LMNAPTGS1
SCHEMBL7187697 0.90 FABP3 (0.48) FABP3FABP4MAPTSMN1; SMN2LMNA
SCHEMBL27437106 0.88 L3MBTL1 (0.41) FABP3FABP4SMN1; SMN2LMNAPTGS1
SCHEMBL7178023 0.87 SMN1; SMN2 (0.41) MAPTSMN1; SMN2ABCC4LMNAGAA
SCHEMBL7179880 0.84 L3MBTL1 (0.35) MAPTSMN1; SMN2LMNAL3MBTL1CCR5
SCHEMBL7181842 0.84 MYC (0.39) FABP3FABP4MAPTSMN1; SMN2LMNA
SCHEMBL7188184 0.83 RXRB (0.42) MAPTSMN1; SMN2LMNA
SCHEMBL7180835 0.83 MEN1 (0.43) SMN1; SMN2LMNAPTGS1L3MBTL1FFAR1
SCHEMBL7185582 0.81 MAPT (0.35) MAPTSMN1; SMN2ABCC4LMNAGAA
SCHEMBL7182551 0.81 LMNA (0.45) FABP3FABP4MAPTSMN1; SMN2ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 FABP3 3252/4885FABP4 4550/4885MAPT 4870/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 FABP3 2807/4885FABP4 4256/4885MAPT 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.