Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | PTPRB | P23467 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049413 | 0.90 | CTSL (0.41) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL7046969 | 0.86 | PTPRB (0.39) | PTPRBPTPN11USP30MAPK1STS | |
| SCHEMBL7047995 | 0.82 | CTSS (0.46) | CTSLCTSBCTSSCTSKKMT2A | |
| SCHEMBL6061657 | 0.81 | PRSS8 (0.43) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL7044976 | 0.79 | PTPRB (0.38) | PTPRBPTPN11USP30MAPK1STS | |
| SCHEMBL6062950 | 0.76 | PRSS8 (0.40) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL6062946 | 0.76 | PRSS8 (0.40) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL6467209 | 0.76 | PRSS8 (0.39) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL7046421 | 0.76 | USP30 (0.39) | CTSLCTSBCTSSCTSKPTPRB | |
| SCHEMBL7046217 | 0.74 | CTSL (0.44) | CTSLCTSBCTSSCTSKPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |