Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PLD2 | O14939 | 2/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184086 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2OPRM1CCRL2HSD11B1 | |
| SCHEMBL7185023 | 0.83 | TNKS (0.54) | ALDH1A1OPRM1HSD11B1USP2LMNA | |
| SCHEMBL7185033 | 0.83 | TNKS (0.54) | ALDH1A1OPRM1HSD11B1USP2LMNA | |
| SCHEMBL28522003 | 0.83 | ALDH1A1 (0.56) | ALDH1A1OPRM1HSD11B1LMNATNKS | |
| SCHEMBL22605771 | 0.83 | ALDH1A1 (0.56) | ALDH1A1OPRM1HSD11B1LMNATNKS | |
| SCHEMBL15289030 | 0.83 | ALDH1A1 (0.56) | ALDH1A1OPRM1HSD11B1LMNATNKS | |
| SCHEMBL22587693 | 0.82 | HSD11B1 (0.56) | ALDH1A1SMN1; SMN2OPRM1HSD11B1LMNA | |
| SCHEMBL15289136 | 0.80 | TNKS (0.46) | ALDH1A1OPRM1USP2LMNATNKS | |
| SCHEMBL7179611 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2OPRM1HSD11B1LMNA | |
| SCHEMBL7179604 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2OPRM1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |