Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756927 | 0.84 | GSK3B (0.34) | MAPK14ACSS2CNR2GSK3BDYRK1A | |
| SCHEMBL2390281 | 0.84 | GSK3B (0.33) | CNR2GSK3BDYRK1A | |
| SCHEMBL6780101 | 0.68 | BRD4 (0.42) | ACSS2MEN1GAAKMT2AOPRM1 | |
| SCHEMBL1986577 | 0.68 | GSK3B (0.43) | MAPK14ACSS2CNR2MEN1GAA | |
| SCHEMBL16447788 | 0.68 | PTGDR2 (0.40) | KDM4ELMNAMAPK14CNR2MEN1 | |
| SCHEMBL5579359 | 0.66 | CYP17A1 (0.46) | MAPK14CYP17A1MAPKAPK2PTGDR2BRD4 | |
| SCHEMBL5579358 | 0.66 | CYP17A1 (0.46) | MAPK14CYP17A1MAPKAPK2PTGDR2BRD4 | |
| SCHEMBL7691178 | 0.66 | LCK (0.47) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL22774622 | 0.65 | CA1 (0.39) | KDM4ELMNAALDH1A1GAACYP17A1 | |
| SCHEMBL18839126 | 0.64 | DRD2 (0.40) | ALDH1A1GFERMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290198-A2 | VECTORS FOR DNA DELIVERY | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001088160-A2 | VECTORS FOR DNA DELIVERY | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI, S.P.A. (IT) | 2001-11-22 | — | — | WO | disclosed |