Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774672 | 0.73 | BRD9 (0.38) | BRD4OPRM1OPRD1OGFRL1NPC1 | |
| SCHEMBL25261543 | 0.68 | BRD4 (0.47) | BRD4OPRM1OPRD1OGFRL1NPC1 | |
| SCHEMBL7184525 | 0.68 | KDM4E (0.35) | BRD4OPRM1OPRD1OGFRL1NPC1 | |
| SCHEMBL14500160 | 0.68 | CYP4Z1 (0.44) | BRD4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6777572 | 0.67 | SIRT2 (0.46) | BRD4OPRM1OPRD1OGFRL1NPC1 | |
| SCHEMBL27402198 | 0.67 | BRD4 (0.53) | BRD4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL25858482 | 0.67 | BRD4 (0.48) | BRD4OPRM1OPRD1OGFRL1NPC1 | |
| SCHEMBL8861190 | 0.66 | OPRM1 (0.58) | BRD4OPRM1OPRD1OGFRL1NPC1 | |
| SCHEMBL29964193 | 0.65 | BCHE (0.49) | BRD4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL18803150 | 0.65 | BCHE (0.49) | BRD4NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683189-B1 | POLYAMIDE-OLIGONUCLEOTIDE CONJUGATES; NETROPSIN AND DISTAMYCIN A SYNTHESIS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-01-27 | — | — | US | disclosed |
| US-6545162-B1 | Solid phase biosynthesis of viricide antibiotic | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-04-08 | — | — | US | disclosed |
| EP-0885189-B9 | METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT | CALIFORNIA INST OF TECHN (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6090947-A | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-18 | — | — | US | disclosed |