Sugi Predict

Sugi Predict / Compounds / SCHEMBL7184558

SCHEMBL7184558

SCHEMBL7184558

O=PCCC(C(=O)c1c(C(F)(F)F)cccc1C(F)(F)F)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 2/20 0.37
▸ PPARG P37231 2/20 0.37
▸ ACP3 P15309 1/20 0.37
▸ TXNRD1 Q16881 1/20 0.36
▸ POLB P06746 4/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ GAA P10253 1/20 0.35
▸ TAS2R14 Q9NYV8 2/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ PTGS2 P35354 1/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ CACNA2D1 P54289 1/20 0.34
▸ CACNA1B Q00975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175913 0.92 EPHX2 (0.36) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7175263 0.91 EPHX2 (0.35) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7187322 0.86 PPARG (0.39) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7189510 0.79 AKR1C3 (0.38) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7189380 0.79 KCNQ2 (0.43) MEN1ALDH1A1KMT2A
SCHEMBL7181114 0.79 L3MBTL1 (0.41) MEN1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL7174905 0.76 CA12 (0.45) POLBMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL7175788 0.76 ACP3 (0.41) PPARGACP3POLBMEN1ALDH1A1
SCHEMBL7182287 0.74 SLC6A2 (0.36) EPHX2MEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL7183549 0.74 KCNQ2 (0.41) ALDH1A1CYP2C9PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 EPHX2 2476/4885PPARG 2956/4885ACP3 4259/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 EPHX2 2048/4885PPARG 2776/4885ACP3 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.