Sugi Predict

Sugi Predict / Compounds / SCHEMBL7175263

SCHEMBL7175263

SCHEMBL7175263

O=PCCCCC(C(=O)c1c(C(F)(F)F)cccc1C(F)(F)F)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 3/20 0.35
▸ PPARG P37231 2/20 0.35
▸ ACP3 P15309 1/20 0.35
▸ TXNRD1 Q16881 1/20 0.34
▸ CCR2 P41597 1/20 0.34
▸ POLB P06746 3/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ SLC7A5 Q01650 2/20 0.33
▸ TGM2 P21980 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ ITGA4 P13612 1/20 0.32
▸ PLK1 P53350 1/20 0.32
▸ PLK3 Q9H4B4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175913 0.96 EPHX2 (0.36) EPHX2PPARGACP3TXNRD1CCR2
SCHEMBL7184558 0.91 EPHX2 (0.37) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7187322 0.83 PPARG (0.39) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7190476 0.81 KCNQ2 (0.40) ALDH1A1CYP2C19
SCHEMBL7177336 0.81 L3MBTL1 (0.38) MEN1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL7175427 0.78 CA12 (0.42) MEN1ALDH1A1KMT2AGAA
SCHEMBL7183606 0.76 KCNQ2 (0.41) MEN1ALDH1A1KMT2ACYP2C19
SCHEMBL7180897 0.76 L3MBTL1 (0.39) MEN1ALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL7189510 0.76 AKR1C3 (0.38) EPHX2PPARGACP3TXNRD1POLB
SCHEMBL7188866 0.76 ALDH1A1 (0.34) EPHX2MEN1ALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 EPHX2 2476/4885PPARG 2956/4885ACP3 4259/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 EPHX2 2048/4885PPARG 2776/4885ACP3 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.