Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881483 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL7042497 | 0.80 | HTT (0.42) | MCL1KMT2AL3MBTL1HTT | |
| SCHEMBL4065877 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL6872167 | 0.78 | PLA2G2A (0.51) | MCL1 | |
| SCHEMBL1274290 | 0.77 | MEN1 (0.46) | SMN1; SMN2CDC25BALDH1A1POLBMEN1 | |
| SCHEMBL6873797 | 0.76 | GAA (0.45) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL25196987 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL30047417 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL4812280 | 0.74 | AKR1C3 (0.45) | SMN1; SMN2KDM4EALDH1A1HPGDAKR1C3 | |
| SCHEMBL7681591 | 0.73 | CXCR5 (0.48) | SMN1; SMN2CDC25BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351922-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055480-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | MAX PLANCK GESELLSCHAFT (DE) | 2002-07-18 | — | — | WO | disclosed |