Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188133 | 0.95 | DUT (0.43) | DUTHSD11B1TDP1TSHRCES2 | |
| SCHEMBL7195643 | 0.89 | DUT (0.39) | DUTHSD11B1TDP1CES2CES1 | |
| SCHEMBL7190329 | 0.84 | DUT (0.43) | DUTTDP1TSHRCES2CES1 | |
| SCHEMBL7195124 | 0.84 | DUT (0.44) | DUTHDAC1HDAC2TDP1ALDH1A1 | |
| SCHEMBL7191495 | 0.83 | DUT (0.43) | DUTHDAC1HDAC2TDP1ALDH1A1 | |
| SCHEMBL7190570 | 0.82 | DUT (0.46) | DUTHDAC1HDAC2TDP1TSHR | |
| SCHEMBL7190867 | 0.81 | CES2 (0.42) | DUTTDP1TSHRCES2CES1 | |
| SCHEMBL7194972 | 0.79 | DUT (0.46) | DUTTDP1TSHRCES2CES1 | |
| SCHEMBL5000451 | 0.78 | DUT (0.43) | DUTHDAC1HDAC2TDP1PPARA | |
| SCHEMBL7190978 | 0.78 | CES2 (0.45) | TDP1TSHRCES2CES1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | claimed |
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | disclosed |