Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185042 | 0.95 | DUT (0.43) | DUTHSD11B1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7195643 | 0.90 | DUT (0.39) | DUTHSD11B1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7190329 | 0.89 | DUT (0.43) | DUTSMN1; SMN2ALDH1A1RAB9ARECQL | |
| SCHEMBL7190570 | 0.87 | DUT (0.46) | DUTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7194972 | 0.83 | DUT (0.46) | DUTALDH1A1LMNATSHRHPGD | |
| SCHEMBL7190867 | 0.83 | CES2 (0.42) | DUTALDH1A1RECQLLMNATSHR | |
| SCHEMBL7190720 | 0.79 | DUT (0.43) | DUTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL7184125 | 0.79 | CES2 (0.40) | DUTSMN1; SMN2ALDH1A1RAB9ARECQL | |
| SCHEMBL7195124 | 0.79 | DUT (0.44) | DUTALDH1A1TDP1MAPT | |
| SCHEMBL7195797 | 0.77 | CES2 (0.44) | ALDH1A1RECQLTSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | claimed |
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | disclosed |