Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931704 | 0.82 | ALDH1A1 (0.47) | POLBPGRRAB9AMEN1KMT2A | |
| SCHEMBL29519164 | 0.81 | PGR (0.42) | POLBPGRRAB9AMAPTALDH1A1 | |
| SCHEMBL19693888 | 0.79 | MAPT (0.41) | PGRRAB9AMEN1KMT2AMAPT | |
| SCHEMBL23032910 | 0.79 | MAPT (0.41) | POLBPGRRAB9AMEN1KMT2A | |
| SCHEMBL7191283 | 0.76 | FLT3 (0.42) | PGRRAB9AMAPTTDP1 | |
| SCHEMBL7191331 | 0.75 | MAPT (0.35) | MAPT | |
| SCHEMBL7187351 | 0.75 | PGR (0.38) | POLBPGRMAPT | |
| SCHEMBL7178509 | 0.75 | PGR (0.38) | POLBPGRMAPT | |
| Hydrochloric Acid SCHEMBL9725423 | 0.75 | RAB9A (0.43) | PGRRAB9AMAPTTDP1 | |
| SCHEMBL24993097 | 0.74 | CCR4 (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |