Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256072 | 0.90 | CYP2D6 (0.60) | OXTRTAS1R3TAS1R1TRPM8KDM4E | |
| SCHEMBL31060243 | 0.83 | FLT3 (0.71) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL12095319 | 0.82 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDFLT3 | |
| SCHEMBL5806070 | 0.81 | TAS1R3 (0.62) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL1287553 | 0.81 | KDM4E (0.66) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL29527237 | 0.81 | KDM4E (0.66) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL335319 | 0.81 | KDM4E (0.66) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL446971 | 0.80 | TAS1R3 (0.64) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL11498190 | 0.80 | KDM4E (0.64) | TAS1R3TAS1R1KDM4EALDH1A1CA2 | |
| SCHEMBL8311483 | 0.80 | TAS1R3 (0.60) | OXTRTAS1R3TAS1R1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220133698-A1 | a-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2022-05-05 | — | — | US | disclosed |
| US-8436043-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20120270865-A2 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | OXTR 2039/4885TAS1R3 2984/4885TAS1R1 2620/4885 |
| US-20220133698-A1 | a-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD | SNCA, HTT, PARK7 | OXTR 2472/4885TAS1R3 754/4885TAS1R1 1197/4885 |
| US-20120270865-A2 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | OXTR 2039/4885TAS1R3 2984/4885TAS1R1 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.