Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9070577 | 0.95 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL27513924 | 0.86 | GPR3 (0.35) | GPR3 | |
| Hydrochloric Acid SCHEMBL2046071 | 0.85 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL7949442 | 0.85 | GPR3 (0.32) | GPR3 | |
| Methane SCHEMBL6557734 | 0.84 | GAA (0.38) | POLB | |
| Hydrochloric Acid SCHEMBL3682096 | 0.83 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL78567 | 0.82 | POLB (0.33) | GPR3POLB | |
| Hydrochloric Acid SCHEMBL8854019 | 0.82 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL979995 | 0.82 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL819707 | 0.82 | MEN1 (0.31) | GPR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6524985-B1 | Organoboroaluminum reaction product of an alkylboronic acid and an alkylaluminum halide, alkylaluminum hydride or alkylaluminum siloxide | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-02-25 | — | — | US | disclosed |
| EP-0601830-B1 | Catalyst components for polymerization of olefins and use thereof | MITSUBISHI CHEM CORP (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5648440-A | ALUMINUM-BORON COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0598543-B1 | Method for producing Alpha-olefin polymers | MITSUBISHI CHEM CORP (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5449650-A | Catalyst components for polymerization of olefins and use thereof | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5346925-A | Method for producing α-olefin polymers | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0601830-A2 | Catalyst components for polymerization of olefins and use thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0598543-A2 | Method for producing Alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1994-05-25 | — | — | EP | disclosed |