Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3732046 | 0.85 | GSK3B (0.30) | — | |
| Hydrochloric Acid SCHEMBL6234366 | 0.83 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5609567 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3270208 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL3734808 | 0.79 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3735435 | 0.77 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL7194046 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3737464 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7191794 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6441415 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0982328-B1 | Propylene resin compositions, process for the preparation thereof, and use thereof. | IDEMITSU PETROCHEMICAL CO (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-20020072569-A1 | Polyolefin resin modifier, polyolefin resin composition and oriented polyolefin film | IDEMITSU PETROCHEMICAL CO., LTD. | 2002-06-13 | — | — | US | disclosed |
| US-6339128-B1 | PACKAGING, THICKNESS ACCURACY OF THE FORMED FILM AND STRETCHABILITY | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-01-15 | — | — | US | disclosed |
| US-6268063-B1 | BLEND OF POLYPROPYLENE AND ETHYLENE-PROPYLENE COPOLYMER;FLEXIBILITY, RADIATION TRANSPARENT | TOKUYAMA CORPORATION (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1041114-A1 | Polyolefin resin modifier, polyolefin resin composition and oriented polyolefin film | TOKUYAMA CORPORATION (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-0982328-A1 | Propylene resin compositions, process for the preparation thereof, and use thereof. | TOKUYAMA CORPORATION (JP) | 2000-03-01 | — | — | EP | disclosed |