Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380819 | 0.83 | KDM4E (0.54) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL7186275 | 0.73 | KDM4E (0.46) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL25758177 | 0.70 | KDM4E (0.63) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL13801324 | 0.68 | KDM4E (0.64) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL3256692 | 0.68 | KDM4E (0.83) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL30415306 | 0.68 | KDM4E (0.83) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| Hydrochloric Acid SCHEMBL27732898 | 0.67 | KDM4E (0.81) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL11577771 | 0.66 | LMNA (0.44) | KDM4EALDH1A1POLBADRA1DHTR2C | |
| SCHEMBL11039324 | 0.66 | KDM4E (0.58) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL30909145 | 0.66 | KDM4E (0.58) | KDM4EBRD4ALDH1A1POLBCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808313-B1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-13 | — | — | EP | disclosed |