Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672648 | 0.74 | ALDH1A1 (0.43) | ATMAHRCYP3A4MAPTGPR84 | |
| SCHEMBL16322764 | 0.71 | HSD17B10 (0.47) | ATMAHRCYP3A4MAPTGPR84 | |
| SCHEMBL5492669 | 0.71 | BCHE (0.40) | TDP1ADKHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL1257288 | 0.70 | RAB9A (0.52) | MAPTMEN1KMT2ATDP1CA1 | |
| SCHEMBL5750914 | 0.70 | KDM4E (0.45) | ATMCYP3A4MAPTKMT2ANQO2 | |
| SCHEMBL718222 | 0.70 | ALDH1A1 (0.41) | MAPTMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL4309887 | 0.69 | PARP1 (0.36) | CYP3A4MAPTMEN1KMT2ATDP1 | |
| SCHEMBL7781750 | 0.69 | HTR2B (0.42) | CA1CA2CYP1A2 | |
| SCHEMBL3835052 | 0.68 | CNR1 (0.33) | ATMHSD17B10ALDH1A1GPR3 | |
| SCHEMBL6721218 | 0.68 | IMPDH2 (0.47) | MAPTMEN1KMT2AIMPDH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576642-B2 | Inhibitors of the production of Ig E antibodies, antiallergens | KOWA CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |