SCHEMBL7186528

SCHEMBL7186528

O=Cc1ccc2c(c1)OC(=O)OC(=O)O2

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP2A6 P11509 5/20 0.41
PTGS2 P35354 2/20 0.39
KDM4E B2RXH2 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.35
ALDH5A1 P51649 2/20 0.33
ABAT P80404 2/20 0.33
AOX1 Q06278 1/20 0.32
TRIM24 O15164 1/20 0.32
HPGD P15428 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
AHR P35869 2/20 0.32
ALDH3A1 P30838 1/20 0.32
ALDH1A3 P47895 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23775788 0.87 ALDH1A1 (0.59) ALDH1A1HSD17B10TDP1CYP2A6PTGS2
SCHEMBL6489263 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10TDP1CYP2A6PTGS2
SCHEMBL2456367 0.73 PTPRC (0.38) PTGS2RAB9AAHR
SCHEMBL18536089 0.72 CYP2A6 (0.55) ALDH1A1HSD17B10TDP1CYP2A6RAB9A
SCHEMBL9874879 0.70 MAOB (0.40) ALDH1A1KDM4E
SCHEMBL22863710 0.70 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1CYP2A6PTGS2
SCHEMBL7187760 0.70 CYP3A4 (0.45) ALDH1A1TDP1KDM4EHPGD
SCHEMBL5711966 0.70 MAPT (0.42) ALDH1A1HSD17B10TDP1KDM4ERAB9A
SCHEMBL2798568 0.70 ALDH1A1 (0.55) ALDH1A1HSD17B10TDP1CYP2A6PTGS2
SCHEMBL23501057 0.68 ALDH1A1 (0.53) ALDH1A1HSD17B10TDP1CYP2A6PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed