Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403676 | 0.88 | GCG (0.38) | GCGHPGDHTTNPSR1NTSR1 | |
| SCHEMBL717967 | 0.84 | SLC6A9 (0.35) | GCG | |
| SCHEMBL720098 | 0.83 | GCG (0.34) | GCGNTSR1 | |
| SCHEMBL716676 | 0.83 | HPGD (0.35) | GCGHPGDHTTNPSR1NTSR1 | |
| SCHEMBL27834231 | 0.79 | NTSR1 (0.38) | GCGHPGDHTTNPSR1NTSR1 | |
| SCHEMBL717389 | 0.79 | GCG (0.41) | GCGHPGDHTTNPSR1NTSR1 | |
| SCHEMBL718463 | 0.78 | GCG (0.34) | GCGHPGDHTTNPSR1NTSR1 | |
| SCHEMBL27834377 | 0.78 | GCG (0.40) | GCGHPGDHTTNPSR1NTSR1 | |
| SCHEMBL716518 | 0.76 | ALDH1A1 (0.40) | GCG | |
| SCHEMBL2669797 | 0.76 | SLC6A9 (0.42) | GCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | GCG 35/4885HPGD 486/4885HTT 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.