Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916340 | 1.00 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL20473230 | 1.00 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL14777839 | 0.90 | CYP1A2 (0.60) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL2721298 | 0.90 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL2721300 | 0.90 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL14777840 | 0.90 | CYP1A2 (0.60) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| Ethyl Acetate SCHEMBL6670678 | 0.89 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL14788874 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL14788877 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL2564729 | 0.88 | PPARA (0.48) | CYP1A2CYP2C9CYP2C19HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111727190-B | Pyridylimidazole benzodiazepine Zhuo Bingsuan ester compound and synthesis and application thereof | 杭州奥默医药股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-108137606-B | Short-acting benzodiazepine derivatives, method for the production thereof and use thereof | 四川科伦博泰生物医药股份有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-106892924-B | Short-acting benzodiazepine derivatives, method for the production thereof and use thereof | 四川科伦博泰生物医药股份有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-108863888-A | The preparation method of one kind (s) -1- (tertbutyloxycarbonyl) -5- oxygen pyrrolidines -2- carboxylic acid, ethyl ester | 吉尔生化（上海）有限公司 | 2018-11-23 | — | — | CN | disclosed |
| US-20180312511-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2018-11-01 | — | — | US | disclosed |
| EP-3363801-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2018-08-22 | — | — | EP | disclosed |
| US-8664203-B2 | Thiazole derivatives and their use as P2Y12 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-03-04 | — | — | US | disclosed |
| US-20130281406-A2 | THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-10-24 | — | — | US | disclosed |
| US-20120053149-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-03-01 | — | — | US | disclosed |
| CN-1185008-C | Therapeutic compositions containing glutathione analogs | TELIK INC (US) | 2005-01-19 | — | — | CN | disclosed |
| CN-1342084-A | Therapeutic compositions containing glutathione analogs | TELIK INC (US) | 2002-03-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053149-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | P2RY12, P2RY1, P2RY2 | CYP1A2 1032/4885CYP2C9 928/4885CYP2C19 591/4885 |
| US-20180312511-A1 | SHORT-ACTING BENZODIAZEPINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | GABRA5, GABRA1, GABRA6 | CYP1A2 119/4885CYP2C9 117/4885CYP2C19 50/4885 |
| US-20130281406-A2 | THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS | P2RY12, P2RY1, P2RY2 | CYP1A2 1022/4885CYP2C9 855/4885CYP2C19 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.