Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.38 |
| ▸ | LIPC | P11150 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045925 | 0.90 | CTSS (0.36) | CTSSKDM4ECYP3A4CYP2C9HTT | |
| SCHEMBL7045927 | 0.90 | CTSS (0.38) | CTSSLIPCLIPGKDM4ECYP3A4 | |
| SCHEMBL7114802 | 0.89 | LMNA (0.38) | CTSSKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6464598 | 0.87 | CTSS (0.35) | CTSSKDM4ECYP3A4CYP2C9HTT | |
| SCHEMBL6464428 | 0.87 | CTSS (0.39) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL7043175 | 0.85 | DAGLA (0.46) | CTSSLIPCLIPGKDM4EHTT | |
| SCHEMBL7046398 | 0.85 | XDH (0.38) | CTSSKDM4ECYP3A4CYP2C9 | |
| SCHEMBL6467366 | 0.84 | DAGLA (0.47) | LIPCLIPGKDM4EHTTMEN1 | |
| SCHEMBL6463188 | 0.84 | DAGLA (0.48) | LIPCLIPGKDM4EHTTMEN1 | |
| SCHEMBL7044329 | 0.82 | KDM4E (0.38) | CTSSLIPCLIPGKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |