Sugi Predict

Sugi Predict / Compounds / SCHEMBL7187734

SCHEMBL7187734

SCHEMBL7187734

CCOc1ccc(PC(=O)c2c(C)cc(C)c(C)c2C)c(C)c1.[LiH]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.37
▸ GAA P10253 2/20 0.37
▸ KDM4E B2RXH2 5/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ MAPT P10636 2/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ HPGD P15428 4/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.35
▸ CYP1A2 P05177 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ SLC5A1 P13866 1/20 0.34
▸ SLC5A2 P31639 1/20 0.34
▸ PARP10 Q53GL7 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ AKR1C3 P42330 1/20 0.34
▸ AKR1C2 P52895 1/20 0.34
▸ NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7186989 0.90 THRB (0.40) KDM4ESMN1; SMN2CYP1A2BRD4
SCHEMBL7188392 0.90 MAPT (0.38) ALDH1A1GAAKDM4ESMN1; SMN2MAPT
SCHEMBL7185613 0.90 KDM4E (0.43) ALDH1A1GAAKDM4ESMN1; SMN2MAPT
SCHEMBL7189173 0.89 FFAR1 (0.38) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL7180663 0.88 THRB (0.43) TSHR
Lithium SCHEMBL7185624 0.88 KDM4E (0.43) ALDH1A1GAAKDM4ESMN1; SMN2MAPT
SCHEMBL7188478 0.88 XDH (0.39) ALDH1A1GAAKDM4ESMN1; SMN2MAPT
SCHEMBL7181568 0.87 THRB (0.45) TSHR
SCHEMBL7175989 0.87 ALDH1A1 (0.39) ALDH1A1GAAKDM4ESMN1; SMN2MAPT
SCHEMBL7183843 0.86 KDM4E (0.38) ALDH1A1KDM4ESMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ALDH1A1 3416/4885GAA 4753/4885KDM4E 3226/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885GAA 4793/4885KDM4E 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.