Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190900 | 0.81 | — | — | |
| SCHEMBL7188473 | 0.75 | PTPN1 (0.48) | PTPN1 | |
| SCHEMBL7595416 | 0.72 | PTPN1 (0.45) | PTPN1 | |
| SCHEMBL7660739 | 0.70 | PGK1 (0.59) | PTPN1 | |
| SCHEMBL5488518 | 0.69 | — | — | |
| SCHEMBL7183073 | 0.69 | PGK1 (0.40) | PTPN1 | |
| SCHEMBL7591720 | 0.69 | PGK1 (0.57) | PTPN1 | |
| SCHEMBL7198006 | 0.68 | PTPN1 (0.42) | PTPN1 | |
| SCHEMBL7663140 | 0.68 | PTPN1 (0.44) | PTPN1 | |
| SCHEMBL7179735 | 0.67 | PTPN1 (0.56) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268494-A1 | SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS | Merck Frosst Canada & Co. (CA) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070753-A1 | SULFUR SUBSTITUTED ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS AS PTP-1B INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2001-09-27 | — | — | WO | disclosed |