Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13581610 | 0.85 | MAPT (0.71) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL92222 | 0.82 | RAB9A (0.65) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL2305268 | 0.81 | MAPT (0.66) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL1962893 | 0.81 | MAPT (0.66) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL7176198 | 0.80 | POLB (0.54) | MAPTPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11605847 | 0.78 | MAPT (0.54) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL11606786 | 0.78 | RAB9A (0.55) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL4449040 | 0.78 | TAS1R3 (0.69) | MAPTPKMKMT2AMEN1RAB9A | |
| SCHEMBL29370034 | 0.77 | RAB9A (0.50) | MAPTPKMGAAKMT2AMEN1 | |
| SCHEMBL15635248 | 0.77 | MAPT (0.47) | MAPTPKMGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366116-A2 | POLYPROPYLENE RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002046300-A2 | POLYPROPYLENE RESIN COMPOSITIONS | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2002-06-13 | — | — | WO | disclosed |